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Metameter:
Pharmaceutical Terms


 
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Metameter:

Metameter:

A term used to designate "the measurement or transformation of the measurement used in evaluating biological tests." Examples of metameters of dose include "milligrams," "moles," "log milligrams," "log milligrams per kilogram of body weight," etc. Metameters of response include "increase in blood pressure, in mmHg," "Maximum blood pressure achieved, in mmHg," and "percent increase in blood pressure." Metameters are frequently and erroneously chosen only to facilitate statistical summary and analysis of data; the metameter used may also obscure or influence the biological interpretation of the data in a manner not intended or expected by the investigator. For example, implicit in the calculation of "percent change in blood pressure " is the statement that the final state of the system is a function of the initial state that may or may not be true.

Cf. Parameter, Bioassay, Dose-Effect Curve

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Copyright 2006. Keith P. Graham