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Dissolution Time:
Dissolution Time:
The time required for a given amount (or fraction) of drug to be released into solution from a solid dosage form. Dissolution time is measured in vitro, under conditions that simulate those that occur in vivo, in experiments in which the amount of drug in solution is determined as a function of time. Needless to say, the availability of a drug in solution - rather than as part of insoluble particulate matter - is a necessary preliminary to the drug's absorption.
Cf. Disintegration Time , Bioavailability , Generic Drug , Biopharmaceutics
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