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Cl, Clx:
Pharmaceutical Terms


 
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Cl, Clx:

Cl, Clx:

Clearance - in volume/unit time - of a drug or chemical from a body fluid, usually plasma or blood, by specified route(s) and mechanism(s) of elimination, as indicated by a subscript, e.g., ClR, urinary clearance; ClH, hepatic clearance, etc. ClT, total clearance, indicates clearance by all routes and mechanisms of biotransformation and excretion, operating simultaneously. ClT = kel · Vd. Following intravenous administration, ClT = D/AUC; following administration of drug by any route other than the intravenous, ClT = F D/AUC.

Cf. Clearance , AUC , F

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Copyright 2006. Keith P. Graham