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b:
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b:

b:

The later segment of a biphasic plot of log C against t (following intravenous injection of a drug) represents the "elimination phase" of the drug's sojourn in the body, when eliminative, rather than distributive, processes dominate the rate at which plasma concentrations of drug decrease with the passage of time. b is used as a subscript for pharmacokinetic parameters appropriate to the elimination phase, e.g. t1/2b, Vdb, etc. For systems with more than two phases, the lower case Greek letters following b are used, in order, to designate the third, fourth, etc., phases.

Cf. a, Compartments, Volume of Distribution, Half-Life

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Copyright 2006. Keith P. Graham