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t½:
t½:
The "half-life" of a drug; the amount of time required for the concentration of a drug in, e.g., a body fluid such as plasma, serum, or blood, to be halved. The idea of half-life is legitimately applied only to the case of a drug eliminated from body fluid according to the laws of first-order reaction kinetics. t½ = 0.301/b = 0.693/kel, where 0.301 and 0.693 are the logarithms of 2 to the bases 10 and e, respectively.
Cf. Half-Life, b, kel, First-Order Kinetics
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