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Potentiation:
Pharmaceutical Terms


 
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Potentiation:

Potentiation:

A special case of synergy (q.v.) in which the effect of one drug is increased by another drug that by itself has no effect. For example, although physostigmine has no acetylcholine-like activity of its own, it potentiates the actions of acetylcholine by inhibiting the enzymes responsible for the destruction of acetylcholine. Intensity of effect may be potentiated, duration of effect may be prolonged: potentiation and prolongation are independent phenomena, but frequently occur together.

Cf. Synergy, Antagonism

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Copyright 2006. Keith P. Graham