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Positive Control Drug:
Positive Control Drug:
A drug preparation incorporated into an experiment with the intention that it have effects on the experimental system qualitatively similar to those expected of the independent variable. The positive control drug has two functions in an experiment: 1) to verify that the experimental system is indeed capable of undergoing the changes expected to follow manipulation of the independent variable. If the system fails to respond to the positive control drug, its failure to respond to the independent variable is uninterpretable; 2) to serve as a basis for quantitative estimation of the relative efficacy of the independent variable. In these terms, the positive control drug is a "standard", and the independent variable may be considered the " unknown" in a bioassay.
Cf. Negative Control Drug, Bioassay, Cross-Over Experiment, Reference Standard
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